Polysorbates like PS20 and PS80 protect proteins from surface stress — until they don’t.
When they degrade, free fatty acids form and start to precipitate, changing the particle landscape and destabilizing your formulation.
At SizeID.bio, we make those pathways visible. Using Raman + MDRS, we detect and identify degradation products directly in your biopharmaceutical injectables — linking chemistry, morphology, and formulation design.

Beyond simple detection, our MDRS-based approach lets you follow these changes over time — directly on the particle level. We can distinguish proteinaceous particles (PPs) from silicone oil droplets (SiOPs), polysorbate degradation products (PDPs), or other subvisible particles (SVPs), providing a full picture of how your formulation evolves under stress. This particle-resolved view supports stability studies, comparability assessments, and root-cause investigations — with ISO-traceable data you can rely on from development through the commercial lifecycle.